Description

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96wellcartridge

• Multipleexperimentsonsingleslide
• Multiplecelltypes,treatmenttimes,andDNArepairtimes
• Screenmultiplegenotoxins
• ParallelProcessing–easeofhandlingsavestimeandreagents
• Easydeterminationofmeanbetweenreplicateswithstandarddeviation

Ge,Jingetal.“MicropatternedCometAssayEnablesHighThroughputandSensitiveDNADamageQuantification.”Mutagenesis30.1(2015):11–19.

Li,Naetal.“InfluenzaInfectionInducesHostDNADamageandDynamicDNADamageResponsesduringTissueRegeneration.”Cellularandmolecularlifesciences :CMLS72.15(2015):2973–2988.

Ge,Jingetal.“CometChip:AHigh-Throughput96-WellPlatformforMeasuringDNADamageinMicroarrayedHumanCells.”JournalofVisualizedExperiments :JoVE92(2014):50607.

Sotiriou,GeorgiosA.etal.“EngineeringSafer-by-Design,Transparent,Silica-CoatedZnONanorodswithReducedDNADamagePotential.”Environmentalscience.Nano1.2(2014):144–153.

Watson,Christaetal.“High-ThroughputScreeningPlatformforEngineeredNanoparticle-MediatedGenotoxicityUsingCometChipTechnology.”ACSNano8.3(2014):2118–2133.

Ge,Jingetal.“StandardFluorescentImagingofLiveCellsIsHighlyGenotoxic.”Cytometry.PartA :thejournaloftheInternationalSocietyforAnalyticalCytology83.6(2013):552–560.

Weingeist,DavidM.etal.“Single-CellMicroarrayEnablesHigh-ThroughputEvaluationofDNADouble-StrandBreaksandDNARepairInhibitors.”CellCycle12.6(2013):907–915.

Chao,Ming-Weietal.“Genotoxicityof2,6-and3,5-DimethylanilineinCulturedMammalianCells:TheRoleofReactiveOxygenSpecies.”ToxicologicalSciences130.1(2012):48–59.

Mutamba,JamesT.etal.“XRCC1andBaseExcisionRepairBalanceinResponsetoNitricOxide.”DNArepair10.12(2011):1282–1293.

Wood,DavidK.etal.“SingleCellTrappingandDNADamageAnalysisUsingMicrowellArrays.”ProceedingsoftheNationalAcademyofSciencesoftheUnitedStatesofAmerica107.22(2010):10008–10013.