Description

ANTIBODYCONCENTRATION
1mg/mlin1XPBScontaining50%glycerol.
ThismonoclonalantibodyisanIgG3purifiedfrommouseascites.
IMMUNOGEN
PurifiedADP-ribosepolymersbetween2and50unitslong.
SPECIFICITY
PARpolymers2to50unitslong
STORAGE
Storeantibodyat-20°Cinamanualdefrostfreezer.
APPLICATIONS
ELISA,WesternBlotAnalysis,immunoprecipitation,andimmunopurification

PARP1-TDP1couplingfortherepairoftopoisomeraseI-inducedDNAdamage,
BenuBrataDas,Shar-yinN.Huang,JunkoMurai,IshitaRehman,Jean-ChristopheAmé,SouvikSengupta,SubhenduK.Das,PapiyaMajumdar,HongliangZhang,DenisBiard,HemantaK.Majumder,ValérieSchreiber,andYvesPommier
NucleicAcidsRes.,Apr2014;42:4435–4449.
http://nar.oxfordjournals.org/cgi/content/abstract/42/7/4435

DNAdouble-strandbreakspromotemethylationofhistoneH3onlysine9andtransientformationofrepressivechromatin
MarinaK.Ayrapetov,OzgeGursoy-Yuzugullu,ChangXu,YeXu,andBrendanD.Price
PNAS,Jun2014;111:9169–9174.
http://www.pnas.org/cgi/content/abstract/111/25/9169

Poly(ADP-ribose)Polymerase1(PARP1)AssociateswithE3Ubiquitin-ProteinLigaseUHRF1andModulatesUHRF1BIOLOGicalFunctions
“MikeDeVos,RosyElRamy,DelphineQuénet,PatriciaWolf,FABIoSpada,NajatMagroun,Federica
Babbio,ValérieSchreiber,HeinrichLeonhardt,IanMarcBonapace,andFrançoiseDantzer”
J.Biol.Chem.,Jun2014;289:16223–16238.
http://www.jbc.org/cgi/content/abstract/289/23/16223

Poly(ADP-Ribose)Polymerase-1CausesMitochondrialDamageandNeuronDeathMediatedbyBnip3
PingLu,AmitKamboj,SpencerB.Gibson,andChristopherM.Anderson
J.Neurosci.,Nov2014;34:15975–15987.
http://www.jneurosci.org/cgi/content/abstract/34/48/15975

The3′-5′DNAExonucleaseTREX1DirectlyInteractswithPoly(ADP-ribose)Polymerase-1(PARP1)duringtheDNADamageResponse
TakuyaMiyazaki,Yong-SooKim,JeongheonYoon,HongshengWang,TeruhikoSuzuki,andHerbertC.Morse,III
J.Biol.Chem.,Nov2014;289:32548–32558.
http://www.jbc.org/cgi/content/abstract/289/47/32548

Aag-initiatedbaseexcisionrepairpromotesischemiareperfusioninjuryinliver,brain,andkidney
MohammadR.Ebrahimkhani,AliDaneshmand,AprotimMazumder,MariacarmelaAllocca,JenniferA.Calvo,NonaAbolhassani,InyJhun,SureshkumarMuthupalani,Cenk
Ayata,andLeonaD.SamsonPNAS,Nov2014;111:E4878–E4886.
http://www.pnas.org/cgi/content/abstract/111/45/E4878

Poly-ADPribosylationofPTENbytankyrasespromotesPTENdegradationandtumorgrowth
NanLi,YajieZhang,XinHan,KeLiang,JiadongWang,LinFeng,WenqiWang,ZhouSongyang,ChunruLin,LiuqingYang,YonghaoYu,andJunjieChen
Genes&Dev.,Jan2015;29:157–170
http://genesdev.cshlp.org/cgi/content/abstract/29/2/157

SUMOylationRegulatesPolo-likeKinase1-interactingCheckpointHelicase(PICH)duringMitosis
VinidhraSridharan,HyewonPark,HyunjuRyu,andYoshiakiAzuma
J.Biol.Chem.,Feb2015;290:3269–3276.
http://www.jbc.org/cgi/content/abstract/290/6/3269

“GENOMEINTEGRITY,REPAIRANDREPLICATION:
TheXRCC1phosphate-bindingpocketbindspoly(ADP-ribose)andis
requiredforXRCC1function”
“ClaireBreslin,PeterHornyak,AndrewRidley,StuartL.Rulten,HanaHanzlikova,AntonyW.Oliver,and
KeithW.Caldecott”
NucleicAcidsRes.,Aug2015;43:6934–6944.
http://nar.oxfordjournals.org/cgi/content/abstract/43/14/6934

“ThePINdomainofEXO1recognizespoly(ADP-ribose)inDNAdamage
response”
FengZhang,JiazhongShi,Shih-HsunChen,ChunjingBian,andXiaochunYu
NucleicAcidsRes.,Sep2015;10.1093/nar/gkv939.
http://nar.oxfordjournals.org/cgi/content/abstract/gkv939v1

“Poly(ADP-ribosyl)ationofMethylCpGBindingDomainProtein2
RegulatesChromatinStructure”
AnnetteBecker,PengZhang,LenaAllmann,DanielaMeilinger,BiancaBertulat,DanielEck,MariaHofstaetter,GiodyBartolomei,MichaelO.Hottiger,ValérieSchreiber,HeinrichLeonhardt,andM.CristinaCardoso
J.Biol.Chem.,Mar2016;291:4873–4881
http://www.jbc.org/cgi/content/abstract/291/10/4873

“Distinctgeneticcontrolofhomologousrecombinationrepairof
Cas9-induceddouble-strandbreaks,nicksandpairednicks”
LianneE.M.Vriend,RohitPrakash,Chun-ChinChen,FabioVanoli,FrancescaCavallo,YuZhang,MariaJasin,andPrzemekM.Krawczyk
NucleicAcidsRes.,Mar2016;10.1093/nar/gkw179.
http://nar.oxfordjournals.org/cgi/content/abstract/gkw179v1

p53coordinatesbaseexcisionrepairtopreventgenomicinstability
MattiaPoletto,ArnaudJ.Legrand,SallyC.Fletcher,andGrigoryL.Dianov
NucleicAcidsRes.,Apr2016;44:3165–3175.
http://nar.oxfordjournals.org/cgi/content/abstract/44/7/3165

“HyperthermiaSynergizeswithChemotherapybyInhibitingPARP1-DependentDNAReplicationArrest”
“LeaSchaaf,MatthiasSchwab,ChristophUlmer,SimonHeine,ThomasE.Mürdter,JensO.Schmid,GeorgSauer,WalterE.Aulitzky,andHeikovanderKuip”
CancerRes.,May2016;76:2868–2875.
http://cancerres.aacrjournals.org/cgi/content/abstract/76/10/2868

“APE1/Ref-1facilitatesrecoveryofgrayandwhitematterand
neurologicalfunctionaftermildstrokeinjury”
“R.AnneStetler,YanqinGao,RehanaK.Leak,ZhongfangWeng,YejieShi,LiliZhang,HongjianPu,Feng
Zhang,XiaomingHu,SulaimanHassan,CarolynFerguson,GreggE.Homanics,GuodongCao,MichaelV.L.Bennett,andJunChen”
PNAS,Jun2016;113:E3558–E3567.
http://www.pnas.org/cgi/content/abstract/113/25/E3558

“DistinctgeneticcontrolofhomologousrecombinationrepairofCas9-induceddouble-strandbreaks,nicksandpairednicks”
“LianneE.M.Vriend,RohitPrakash,Chun-ChinChen,FabioVanoli,FrancescaCavallo,YuZhang,Maria
Jasin,andPrzemekM.Krawczyk”
http://nar.oxfordjournals.org/cgi/content/abstract/44/11/5204

“ARADIotracerStrategytoQuantifyPARP-1ExpressionInVivoProvidesaBioMarkerThatCanEnablePatientSelectionforPARP
InhibitorTherapy”
“MehranMakvandi,KuiyingXu,BrianP.Lieberman,Redmond-CraigAnderson,SamuelSanderEffron,
HarrisonD.Winters,ChenboZeng,ElizabethS.McDonald,DanielA.Pryma,RogerA.Greenberg,andRobertH.Mach”
CancerRes.,Aug2016;76:4516–4524.
http://cancerres.aacrjournals.org/cgi/content/abstract/76/15/4516

“NitricOxideSuppressesβ-CellApoptosisbyInhibitingtheDNA
DamageResponse”
“BryndonJ.Oleson,KatarzynaA.Broniowska,AaronNAATz,NeilHogg,VeraL.Tarakanova,andJohnA.Corbett”
Mol.Cell.Biol.,Aug2016;36:2067–2077.
http://mcb.asm.org/cgi/content/abstract/36/15/2067

ANovelRoleofChromodomainProteinCBX8inDNADamageResponse
JayOza,BratatiGanguly,AtulKulkarni,VasudevaGinjala,MingYao,andShridarGanesan
J.Biol.Chem.,Oct2016;291:22881–22893
http://www.jbc.org/cgi/content/abstract/291/44/22881

“PARylationoftheforkhead-associateddomainproteinDAWDLEregulatesplantimmunity”
BaominFeng,ShisongMa,SixueChen,NingZhu,ShuxinZhang,BinYu,YuYu,BrandonLe,XuemeiChen,SavithrammaPDinesh-Kumar,LiboShan,andPingHe
EMBORep.,Oct2016;10.15252/embr.201642486
http://EMBOr.embopress.org/cgi/content/abstract/embr.201642486v1

“FASNregulatescellularresponsetogenotoxictreatmentsby
increasingPARP-1expressionandDNArepairactivityviaNF-Band
SP1”
“XiWu,ZizhengDong,ChaoJ.Wang,LincolnJamesBarlow,ValerieFako,MoisesA.Serrano,YueZou,
Jing-YuanLiu,andJian-TingZhang”
PNAS,Nov2016;113:E6965–E6973
http://www.pnas.org/cgi/content/abstract/113/45/E6965