Description

ANTIBODYCONCENTRATION
Providedin1XPBScontaining50%glycerol.
ThisrabbitpolyclonalantibodyisapurifiedIgGfraction.
IMMUNOGEN
Poly(ADP-ribose)polymer
SPECIFICITY
ThisantibodydetectsfreePARandpoly-ribosylatedproteins.
STORAGE
Storeantibodyat-20°Cinamanualdefrostfreezer.
APPLICATIONS
ELISAandWesternBlotAnalysis

StereospecificPARPTrappingbyBMN673andComparisonwithOlaparibandRucaparib
Murai,J.,Huang,S.N.,Renaud,A.,Zhang,Y.,Ji,J.,Takeda,S.,Morris,J.,Teicher,B.,Doroshow,J.H.,andPommier,Y.,StereospecificPARPTrappingbyBMN673andComparisonwithOlaparibandRucaparib41671MolecularCancerTherapeutics
Mol.CancerTher.,Feb2014;13:433–443
http://mct.aacrjournals.org/cgi/content/abstract/13/2/433

NitricOxideInducesAtaxiaTelangiectasiaMutatedATMProtein-dependentgammaH2AXProteinFormationinPancreaticbetaCells,
BryndonJ.Oleson,KatarzynaA.Broniowska,KatherineH.Schreiber,VeraL.Tarakanova,andJohnA.Corbett
J.Biol.Chem.,Apr2014;289:11454–11464
http://www.jbc.org/cgi/content/abstract/289/16/11454

ABCB1,ABCG2,andPTENDeterminetheResponseofGlioblastomatoTemozolomideandABT-888Therapy
Lin,F.,deGooijer,M.C.,Roig,E.M.,Buil,L.C.M.,Christner,S.M.,Beumer,J.H.,Wurdinger,T.,Beijnen,J.H.andvanTellingen,O.
Clin.CancerRes.,May2014;20:2703–2713.
http://clincancerres.aacrjournals.org/cgi/content/abstract/20/10/2703
RationaleforPoly(ADP-ribose)Polymerase(PARP)InhibitorsinCombinationTherapywithCamptothecinsorTemozolomideBasedonPARPTrappingversusCatalyticInhibition
Murai,J.,Zhang,Y.,Morris,J.,Ji,J.,Takeda,S.,Doroshow,J.H.andPommier,Y.
J.Pharmacol.Exp.Ther.,May2014;349:408–416.
http://jpet.aspetjournals.org/cgi/content/abstract/349/3/408

PARGisdispensableforrecoveryfromtransientreplicativestressbutrequiredtopreventdetrimentalaccumulationofpoly(ADP-ribose)uponprolongedreplicativestress
GiudittaIlluzzi,EliseFouquerel,Jean-ChristopheAmé,AuréliaNoll,KristinaRehmet,Heinz-PeterNasheuer,FrançoiseDantzer,andValérieSchreiber
NucleicAcidsRes.,Aug2014;42:7776–7792
http://nar.oxfordjournals.org/cgi/content/abstract/42/12/7776

HyperthermiaInhibitsRecombinationRepairofGemcitABIne-StalledReplicationForks
MustafaRaoof,CihuiZhu,BrandonT.Cisneros,HepingLiu,StuartJ.Corr,LonJ.Wilson,andStevenA.Curley
JNatlCancerInst,Aug2014;106:dju183
http://jnci.oxfordjournals.org/cgi/content/abstract/106/8/dju183

PARP-2andPARP-3areselectivelyactivatedby5′phosphorylatedDNAbreaksthroughanallostericregulatorymechanismsharedwithPARP-1
Marie-FranceLangelier,AmandaA.Riccio,andJohnM.Pascal
NucleicAcidsRes.,Aug2014;42:7762–7775.
http://nar.oxfordjournals.org/cgi/content/abstract/42/12/7762

RegulationofMitochondrialPoly(ADP-Ribose)PolymeraseActivationbytheβ-Adrenoceptor/cAMP/ProteinKinaseAAxisduringOxidativeStress
AttilaBrunyanszki,GaborOlah,CiroColetta,BartoszSzczesny,andCsabaSzabo
Mol.Pharmacol.,Sep2014;86:450–462.
http://molpharm.aspetjournals.org/cgi/content/abstract/86/4/450

PARP-1MediatesLPS-InducedHMGB1ReleasebyMacrophagesthroughRegulationofHMGB1Acetylation
ZhiyongYang,LiLi,LijuanChen,WeiweiYuan,LimingDong,YushunZhang,HeshuiWu,andChunyouWang
J.Immunol.,Dec2014;193:6114–6123
http://www.jimmunol.org/cgi/content/abstract/193/12/6114

“Femtosecondnear-infraredlasermicroirrADIationrevealsacrucialroleforPARPsignalingonfactorassembliesatDNAdamagesites”
GladysMaeSaquilabonCruz,XiangduoKong,BárbaraAlcarazSilva,NimaKhatibzadeh,RyanThai,MichaelW.Berns,andKyokoYokomori
NucleicAcidsRes.,Sep2015;10.1093/nar/gkv976.
http://nar.oxfordjournals.org/content/early/2015/09/30/nar.gkv976.full

ThePINdomainofEXO1recognizespoly(ADP-ribose)inDNAdamageresponse
FengZhang,JiazhongShi,Shih-HsunChen,ChunjingBian,andXiaochunYu
NucleicAcidsRes.,Dec2015;43:10782–10794.
http://nar.oxfordjournals.org/cgi/content/abstract/43/22/10782

Femtosecondnear-infraredlasermicroirradiationrevealsacrucialroleforPARPsignalingonfactorassembliesatDNAdamagesites
GladysMaeSaquilabonCruz,XiangduoKong,BárbaraAlcarazSilva,NimaKhatibzadeh,RyanThai,MichaelW.Berns,andKyokoYokomori
NucleicAcidsRes.,Feb2016;44:e27
http://nar.oxfordjournals.org/cgi/content/abstract/44/3/e27

“ARadiotracerStrategytoQuantifyPARP-1ExpressionInVivo
ProvidesaBioMarkerThatCanEnablePatientSelectionfoPARP
InhibitorTherapy”
“MehranMakvandi,KuiyingXu,BrianP.Lieberman,Redmond-CraigAnderson,SamuelSanderEffron,
HarrisonD.Winters,ChenboZeng,ElizabethS.McDonald,DanielA.Pryma,RogerA.Greenberg,and
RobertH.Mach”
CancerRes.,Aug2016;76:4516–4524
http://cancerres.aacrjournals.org/cgi/content/abstract/76/15/4516

Poly(ADP-ribose)polymersregulateDNAtopoisomeraseI(Top1)nucleardynamicsandcamptothecinsensitivityinlivingcells
SubhenduK.Das,IshitaRehman,ArijitGhosh,SouvikSengupta,PapiyaMajumdar,BimanJana,andBenuBrataDas
NucleicAcidsRes.,Sep2016;44:8363–8375.
http://nar.oxfordjournals.org/cgi/content/abstract/44/17/8363

TheroleofADP-ribosylationinregulatingDNAinterstrandcrosslinkrepair
AlasdairR.Gunn,BenitoBanos-Pinero,PeggyPaschke,LuisSanchez-Pulido,AntonioAriza,JosephDay,MeheraEmrich,DavidLeys,ChrisP.Ponting,IvanAhel,andNicholasD.Lakin
J.CellSci.,Oct2016;129:3845–3858
http://jcs.BIOLOGists.org/cgi/content/abstract/129/20/3845