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Trevigen/人8-氧胍DNA糖苷酶和10X REC™ 缓冲液6/4130-100-EB/100单位，5 x 100单位，1毫升
Description
CONCENTRATION
100unitspervial
SOURCE
PurifiedfromE.colicontainingarecombinantplasmidharboringtheα-hOGG1gene(nuclearprotein).
SUBSTRATESPECIFICITY
ThecatalyticactivityofhOGG1isdependentuponthebasethe8-oxoGispairedwithintheorderofC>T>G,A. hOGG1isalsocatalyticallyactivewhenFaPyispairedwithC.FaPyisonlyrepairedwhenbasepairedtocytosine.
STORAGE
Storeat-20°Cinamanualdefrostfreezer.Forlong-termstorage,freezeat-80°Cinworkingaliquots.
APPLICATIONS
DNARepairAssays
FLARE™
| Catalog#4130-100-EBincludes: | ||
| CatalogNumber | Description | Qty |
| 3900-500-06 | 10XREC™ReactionBuffer6 | 1 |
| 4130-100-01 | E.colihOGG1 | 1 |
| Catalog#4130-500-EBincludes: | ||
| CatalogNumber | Description | Qty |
| 3900-500-06 | 10XREC™ReactionBuffer6 | 1 |
| 4130-100-01 | E.colihOGG1 | 5 |
“InfluenceofOxidizedPurineProcessingonStrand
DirectionalityofMismatchRepair”
SimoneRepmann,MaiteOlivera-Harris,andJosefJiricny
J.Biol.Chem.,Apr2015;290:9986–9999
http://www.jbc.org/cgi/content/abstract/290/16/9986
FormationandRepairofMismatchesContainingRibonucleotidesandOxidizedBasesatRepeatedDNASequences
PieraCilli,AnnaMinoprio,CeciliaBossa,MargheritaBignami,andFilomenaMazzei
J.Biol.Chem.,Oct2015;290:26259–26269.
http://www.jbc.org/cgi/content/abstract/290/43/26259
OxidizeddNTPsandtheOGG1andMUTYHDNAglycosylasescombinetoinduceCAG/CTGrepeatinstABIlity
PieraCilli,IleniaVentura,AnnaMinoprio,EttoreMeccia,AlbertoMartire,SamuelH.Wilson,MargheritaBignami,andFilomenaMazzei
NucleicAcidsRes.,Mar2016;10.1093/nar/gkw170
http://nar.oxfordjournals.org/cgi/content/abstract/gkw170v1
“OxidizeddNTPsandtheOGG1andMUTYHDNAglycosylasescombine
toinduceCAG/CTGrepeatinstability”
“PieraCilli,IleniaVentura,AnnaMinoprio,EttoreMeccia,AlbertoMartire,SamuelH.Wilson,MargheritaBignami,andFilomenaMazzei”
NucleicAcidsRes.,Jun2016;44:5190–5203.
http://nar.oxfordjournals.org/cgi/content/abstract/44/11/5190
“Weaksilicananomaterial-inducedgenotoxicitycanbeexplainedby
indirectDNAdamageasshownbytheOGG1-modifiedcometassayand
genomicanalysis”
StefanPfuhler,ThomasR.Downs,AshleyJ.Allemang,YuchingShan,andMeredithE.CrosbyMutagenesis,Nov2016;10.1093/mutage/gew064.
http://mutage.oxfordjournals.org/cgi/content/abstract/gew064v1
