Description

FEATURES:

• Speciallytreatedslidestopromoteagaroseadherence
• Readytouselowmeltagarose(LMAgarose)inconvenientsize
• LysisSolutionsuitableforeitheralkalineorneutralcometassay
• Optimizedelectrophoresisconditions

APPLICATIONS:

• Applicablefortheanalysisofeithersingle-ordouble-strandDNAbreaks
• StudycellularresponsestoDNAdamage
• ScreenforinhibitorsofDNArepair
• Testchemicalsfortoxicity
• Screenforenvironmentalmutagens

Aroleforthep53tumoursuppressorinregulatingthebalancebetweenhomologousrecombinationandnon-homologousendjoining
SylvieMoureau,JannaLuessing,EmmaChristinaHarte,MurielVoisin,andNoelFrancisLowndes
OpenBio,Sep2016;6:160225.
http://rsob.royalsocietypublishing.org/cgi/content/abstract/6/9/160225

SpecialAT-richSequence-bindingProtein1(SATB1)FunctionsasanAccessoryFactorinBaseExcisionRepair
SimranKaur,YanCoulombe,ZubaidahM.Ramdzan,LamLeduy,Jean-YvesMasson,andAlainNepveu
J.Biol.Chem.,Oct2016;291:22769–22780
http://www.jbc.org/cgi/content/abstract/291/43/22769

HumanCDK18promotesreplicationstresssignalingandgenomestABIlity
GiancarloBarone,ChristopherJ.Staples,AnilGanesh,KarlW.Patterson,DominicP.Bryne,KatieN.Myers,AbhijitA.Patil,ClaireE.Eyers,SarahMaslen,J.MarkSkehel,PatrickA.Eyers,andSpencerJ.Collis
NucleicAcidsRes.,Oct2016;44:8772–8785
http://nar.oxfordjournals.org/cgi/content/abstract/44/18/8772

AnucleasethatmediatescelldeathinducedbyDNAdamageandpoly(ADP-ribose)polymerase-1
“YingfeiWang,RanAn,GeorgeK.Umanah,HyejinPark,KalyaniNambiar,StephenM.Eacker,BongWoo
Kim,LeiBao,MagedM.Harraz,CalvinChang,RongChen,JenniferE.Wang,Tae-InKam,JunSeop
Jeong,ZhiXie,StewartNeifert,JiangQian,ShaidaA.Andrabi,SethBlackshaw,HengZhu,HongjunSong,
Guo-liMing,ValinaL.Dawson,andTedM.Dawson”
Science,Oct2016;354:aad6872.
http://science.sciencemag.org/cgi/content/abstract/354/6308/aad6872

AmplificationofTLK2InducesGenomicInstabilityviaImpairingtheG2–MCheckpoint
Jin-AhKim,MeenakshiAnurag,JamunaraniVeeraraghavan,RachelSchiff,KaiyiLi,andXiao-SongWang
Mol.CancerRes.,Oct2016;14:920–927
http://mcr.aacrjournals.org/cgi/content/abstract/14/10/920

LongnoncodingRNAPOU6F2-AS2isassociatedwithoesophagealsquamouscellcarcinoma
“JingLiu,XiangdongSun,HongchengZhu,QinQin,XiYang,andXinchenSun”
J.Biochem.,Oct2016;160:195–204.
http://jb.oxfordjournals.org/cgi/content/abstract/160/4/195

LurbinectedinSpecificallyTriggerstheDegradationofPhosphorylatedRNAPolymeraseIIandtheFormationofDNABreaksinCancerCells
GemaSantamaríaNuñez,CarlosMarioGenesRobles,ChristopheGiraudon,JuanFernandoMartínez-Leal,EmmanuelCompe,FrédéricCoin,PabloAviles,CarlosMaríaGalmarini,andJean-MarcEgly
Mol.CancerTher.,Oct2016;15:2399–2412
http://mct.aacrjournals.org/cgi/content/abstract/15/10/2399

TwofamilialALSproteinsfunctioninprevention/repairoftranscription-associatedDNAdamage
SarahJ.Hill,DanielA.Mordes,LisaA.Cameron,DonnaS.Neuberg,SerenaLandini,KevinEggan,andDavidM.Livingston
PNAS,Nov2016;113:E7701–E7709
http://www.pnas.org/cgi/content/abstract/113/48/E7701

Epigeneticeffectsofcarbonnanotubesinhumanmonocyticcells“DenizÖner,MatthieuMoisse,ManosijGhosh,RaduC.Duca,KatrienPoels,KatrienLuyts,Eveline
Putzeys,StevanM.Cokic,KirstenVanLanduyt,JeroenVanoirbeek,DietherLambrechts,LodeGodderis,
andPeterH.M.Hoet”
Mutagenesis,Nov2016;10.1093/mutage/gew053
http://mutage.oxfordjournals.org/cgi/content/abstract/gew053v1

“Distribution,quantificationandtoxicityofcinnamaldehydein
electroniccigaretterefillfluidsandaerosols”
“RachelZBehar,WentaiLuo,SabrinaCLin,YuhuanWang,JackelynValle,JamesFPankow,andPrue
Talbot”
Tob.Control,Nov2016;25:ii94–ii102
http://tobaccocontrol.bmj.com/cgi/content/abstract/25/Suppl_2/ii94