Description
TheXTTCellProliferationAssay(XTT-CPA)isasensitivekitforthemeasurementofcellproliferation.Cleavageofthetetrazoliumsalttoformazanoccursviathesuccinate-tetrazoliumreductasesysteminthemitochondriaofmetabolicallyactivecells.
Features:
- Allowsmeasurementofcellproliferation,cellviABIlityorcytotoxicity.
- Rapiddeterminationinmicroplates(nosolubilizationstepasinanMTTassay).
- ReproducIBLeandsensitiveresults.
- NorADIoactivity.
- Idealforhighthroughputassays(nowashingorotherstepsthatcancausecelllossandvariability).
| Catalog#4891-025-Kincludes: | ||
| CatalogNumber | Description | Qty |
| 4891-025-01 | XTTReagent | 1 |
| 4891-025-02 | XTTActivator | 1 |
Akt-ActivatedEndotheliumConstitutestheNicheforResidualDiseaseandResistancetoBevacizumabinOvarianCancer
BellaS.Guerrouahen,JenniferPasquier,NadineAbuKaoud,MahtabMaleki,Marie-ClaudeBeauchamp,AmberYasmeen,PegahGhiabi,RaphaelLis,FabienVidal,AhmedSaleh,WalterH.Gotlieb,ShahinRafii,andArashRafii
Mol.CancerTher.,Dec2014;13:3123–3136.
http://mct.aacrjournals.org/cgi/content/abstract/13/12/3123
ASpliceVariantoftheHumanIonChannelTRPM2ModulatesNeuroblastomaTumorGrowththroughHypoxia-inducibleFactor(HIF)-1/2{alpha}
Shu-jenChen,NicholasE.Hoffman,SanthanamShanmughapriya,LeiBao,KerryKeefer,KathleenConrad,SalimMerali,YoshinoriTakahashi,ThomasAbraham,IwonaHirschler-Laszkiewicz,JuFangWang,Xue-QianZhang,JianliangSong,CarlosBarrero,YuguangShi,YukaImamuraKawasawa,MichaelBayerl,TianyuSun,MustafaBarbour,Hong-GangWang,MuniswamyMadesh,JosephY.Cheung,andBarbaraA.Miller
J.Biol.Chem.,Dec2014;289:36284–36302.
http://www.jbc.org/cgi/content/abstract/289/52/36284
“DepletionoftheHumanIonChannelTRPM2inNeuroblastoma
DemonstratesItsKeyRoleinCellSurvivalthroughModulationof
MitochondrialReactiveOxygenSpeciesandBioenergetics”
“LeiBao,Shu-jenChen,KathleenConrad,KerryKeefer,ThomasAbraham,JohnP.Lee,JuFangWang,Xue-QianZhang,IwonaHirschler-Laszkiewicz,Hong-GangWang,SinisaDovat,BrianGans,MuniswamyMadesh,JosephY.Cheung,andBarbaraA.Miller”
J.Biol.Chem.,Nov2016;291:24449–24464
http://www.jbc.org/cgi/content/abstract/291/47/24449
